Missoula is a city in the U.S. state of Montana; it is the county seat of Missoula County. It is located along the Clark Fork River near its confluence with the Bitterroot and Blackfoot Rivers in western Montana and at the convergence of five mountain ranges, thus it is often described as the "hub of five valleys". In 2019, the United States Census Bureau estimated the city's population at 75,516 and the population of the Missoula Metropolitan Area at 118,791. After Billings, Missoula is the second-largest city and metropolitan area in Montana. Missoula is home to the University of Montana, a public research university.