Kleine is a German and Dutch surname meaning "small". Notable people with the surname include:Andrea Kleine, American writer, choreographer, and performance artist Christian Kleine, German musician and DJ Cindy Kleine, American film director, producer and video artist George Kleine (1864-1931), American film producer and pioneer Hal Kleine (1923–1957), American baseball pitcher Joe Kleine, American basketball player Lil' Kleine, stage name of Jorik Scholten, Dutch rapper Megan Kleine, American swimmer Piet Kleine, Dutch speed skater Robert Kleine, American Michigan State Treasurer Theodor Kleine (1924–2014), German sprint canoer Thomas Kleine, German football defender and manager