Omaha is the largest city in the U.S. state of Nebraska and the county seat of Douglas County. Omaha is in the Midwestern United States on the Missouri River, about 10 miles (15 km) north of the mouth of the Platte River. The nation's 40th-largest city, Omaha's 2019 estimated population was 478,192, compared to its 2010 census population of 408,958. It is the second-largest city in the Great Plains states, the second-largest city along the Missouri River, and the seventh-largest city in the Midwest.